Blar i forfatter "Zhou, Yan"

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    • Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: A laboratory study using an in vitro model 

      Eksteen, Mariana; Heide, Gøril; Tiller, Heidi; Zhou, Yan; Nedberg, Nora Hersoug; Martinez-Zubiaurre, Inigo; Husebekk, Anne; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar; Kjær, Mette (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-21)
      Background: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disorder caused by maternal antibodies against paternal human platelet antigens (HPAs) on fetal platelets. Antibodies against HPA-1a are accountable for the majority of FNAIT cases. We have previously shown that high levels of maternal anti-HPA-1a antibodies are associated with clinically significant reduced birth ...